Cheng Lan, Huang Qi, Wu Hao, Yang Jun, Chen Li, Zhang Zhihua
Department of Otolaryngology Head and Neck Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, 200092, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Aug;23(15):693-6.
To discuss the diagnosis and treatment of infantile congenital subglottic hemangioma.
Nine patients with recurrent stridor, feeding difficulties and laryngeal obstruction were diagnosed as congenital subglottic hemangioma with bronchial endoscopy. The lesions were unilateral in 7 cases and bilateral in 2 cases. Eight cases were treated by intralesional Pingyangmycin injection after tracheotomy. Patients were discharged with metal trachea and were followed up endoscopically 2 weeks thereafter. A second treatment would be required if the tumor reduced in size but not disappeared completely. Plugging tubes and extubation would be done when the tumor disappeared completely. One case with unilateral lesion underwent power-assisted tumor resection without tracheotomy.
Hemangioma vanished completely in 6 patients with unilateral subglottic hemangioma who were treated with single stage procedure. Tumor size was found reduced significantly after one procedure and vanished completely after a second procedure in 2 cases with bilateral subglottic hemangioma. All of the 8 cases were extubated successfully. The patient recovered thoroughly in two weeks after power-assisted tumor resection.
Intralesional Pingyangmycin injection after tracheotomy can relief the airway obstruction quickly, shorten the nature course of hemangioma, shorten the period of wearing trachea, has no complication such as subglottic stenosis and is thought to be a safe and effective therapy for large size hemangioma. Power-assisted tumor resection under good total anesthesia without tracheotomy combined with well hemostasis is effective, less injure, and suitable for small size hemangioma.
探讨婴幼儿先天性声门下血管瘤的诊断与治疗方法。
对9例反复出现喘鸣、喂养困难及喉梗阻的患儿行支气管镜检查,诊断为先天性声门下血管瘤。其中7例为单侧病变,2例为双侧病变。8例行气管切开后瘤体内注射平阳霉素治疗,术后带金属气管套管出院,2周后行支气管镜复查,若肿瘤缩小但未完全消失则需再次治疗,肿瘤完全消失后拔管堵管。1例单侧病变患儿在全身麻醉下行支撑喉镜下血管瘤切除术,未行气管切开。
6例单侧声门下血管瘤患儿经一期手术治疗后血管瘤完全消失;2例双侧声门下血管瘤患儿经一次治疗后肿瘤明显缩小,二次治疗后完全消失。8例均成功拔管,支撑喉镜下血管瘤切除术后2周患儿痊愈。
气管切开后瘤体内注射平阳霉素可迅速解除气道梗阻,缩短血管瘤自然病程,缩短带管时间,无喉狭窄等并发症,是治疗较大血管瘤安全有效的方法。全身麻醉下支撑喉镜下血管瘤切除术,术中止血良好,未行气管切开,手术损伤小,适用于较小血管瘤。