Dreval' A V, Misnikova I V, Barsukov I A
Ter Arkh. 2009;81(10):34-8.
To evaluate the influence of age and body mass index (BMI) on fasting and postprandial (2 hours after glucose load) plasma glucose (FPG and PPG) levels in males and females.
A screening for carbohydrate metabolic disturbances (by using an oral glucose tolerance test) was made in the stratified adult sample from two municipal districts of the Moscow Region. The data were statistically processed by the computer program SPSS 11.0.
The mean FPG level in normoglycemic subjects was 5.26 +/- 0.43 mmol/l. There was a significant (p < 0.001) positive correlation between age and FPG: r = 0.11 in men and r = 0.17 in women. The mean PPG was 6.15 +/- 1.35 mmol/l; in males it was significantly lower than that in females. There was a significant correlation between age and PPG: r = 0.30 in males and r = 0.13 in females. A weak, but statistically significant correlation was found between FPG and body mass index (BMI) in women: r = 0.02. There was no significant correlation between FPG and BMI in men. No significant correlation was found between PPG and BMI in both males and females. A lower PPG level was 2 times more frequently observed in men than that in women (37.70 and 17.57%, respectively).
Fasting and postprandial (2 hours after glucose load) plasma glucose levels increase with age in subjects without carbohydrate metabolic disturbances. A predictable plasma glucose level increase depending on age is described by the cubic regression model equation.
评估年龄和体重指数（BMI）对男性和女性空腹及餐后（葡萄糖负荷后2小时）血糖（FPG和PPG）水平的影响。
对来自莫斯科地区两个市区的分层成年样本进行碳水化合物代谢紊乱筛查（采用口服葡萄糖耐量试验）。数据用计算机程序SPSS 11.0进行统计处理。
血糖正常受试者的平均空腹血糖水平为5.26±0.43 mmol/l。年龄与空腹血糖之间存在显著正相关（p<0.001）：男性r = 0.11，女性r = 0.17。平均餐后血糖为6.15±1.35 mmol/l；男性显著低于女性。年龄与餐后血糖之间存在显著相关性：男性r = 0.30，女性r = 0.13。女性空腹血糖与体重指数（BMI）之间存在微弱但具有统计学意义的相关性：r = 0.02。男性空腹血糖与BMI之间无显著相关性。男性和女性餐后血糖与BMI之间均无显著相关性。男性餐后血糖水平较低的发生率是女性的2倍（分别为37.70%和17.57%）。
在无碳水化合物代谢紊乱的受试者中，空腹及餐后（葡萄糖负荷后2小时）血糖水平随年龄增长而升高。三次回归模型方程描述了根据年龄可预测的血糖水平升高情况。
