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The interaction of NSBP1/HMGN5 with nucleosomes in euchromatin counteracts linker histone-mediated chromatin compaction and modulates transcription.
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The nucleosome binding protein HMGN3 modulates the transcription profile of pancreatic beta cells and affects insulin secretion.
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Unfoldomics of human diseases: linking protein intrinsic disorder with diseases.
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HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility.
Mol Cell. 2009 Jun 12;34(5):620-6. doi: 10.1016/j.molcel.2009.04.014.
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Nucleosome binding proteins potentiate ATM activation and DNA damage response by modifying chromatin.
Cell Cycle. 2009 Jun 1;8(11):1641. doi: 10.4161/cc.8.11.8569. Epub 2009 Jun 19.
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Expression of nucleosomal protein HMGN1 in the cycling mouse hair follicle.
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Activation of ATM depends on chromatin interactions occurring before induction of DNA damage.
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Delineation of the protein module that anchors HMGN proteins to nucleosomes in the chromatin of living cells.
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