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捷克人群样本中 17 个短串联重复序列的等位基因频率数据。

Allele frequency data for 17 short tandem repeats in a Czech population sample.

机构信息

Institute of Criminalistics Prague, Police of the Czech Republic, P.O. Box 62/KUP, 17082 Praha 7, Czech Republic.

出版信息

Forensic Sci Int Genet. 2009 Dec;4(1):e15-7. doi: 10.1016/j.fsigen.2009.01.003. Epub 2009 Feb 13.

Abstract

Allele frequencies for 17 short tandem repeats (STRs) autosomal loci (D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, CSF1PO, FGA, PentaD, PentaE, TH01, TPOX, vWA) were studied in an extensive sample (max. N=1411) of unrelated individuals originating from the Czech Republic. Population and forensic parameters were estimated. Except for FGA and Penta E loci, no deviations from the Hardy-Weinberg equilibrium were detected. A comparative analysis with published data revealed significant differences in allele frequencies for some loci from the Polish population and three Hungarian populations (Ashkenazim population and Romany populations from Debrecen and Baranya County, respectively). A combination of these 17 STR loci provides a powerful tool for forensic identification in the native Czech population.

摘要

在一项对来自捷克共和国的广泛样本(最大 N=1411)的无关个体进行的研究中,研究了 17 个常染色体短串联重复(STR)位点(D2S1338、D3S1358、D5S818、D7S820、D8S1179、D13S317、D16S539、D18S51、D19S433、D21S11、CSF1PO、FGA、PentaD、PentaE、TH01、TPOX、vWA)的等位基因频率。估计了人口和法医学参数。除了 FGA 和 Penta E 位点外,未检测到 Hardy-Weinberg 平衡的偏离。与已发表的数据进行比较显示,一些来自波兰人群和三个匈牙利人群(阿什肯纳兹人群和分别来自德布勒森和巴兰尼亚县的罗姆人群)的位点的等位基因频率存在显著差异。这 17 个 STR 位点的组合为捷克本土人群的法医鉴定提供了强有力的工具。

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