Núcleo de Diagnóstico e Investigação Molecular (NUDIM), Laboratório de Biotecnologia, Centro de Biociências e Biotecnologia, Universidade Estadual do Norte Fluminense Darcy Ribeiro, Avenida Alberto Lamego 2000, Parque Califórnia, Campos dos Goytacazes CEP 29013-602, RJ, Brazil.
Forensic Sci Int Genet. 2009 Dec;4(1):e25-6. doi: 10.1016/j.fsigen.2009.01.008. Epub 2009 Feb 20.
Allele frequencies data, paternity and forensic parameters for 15 autosomal short tandem repeat (STR) autosomal markers (D8S1179, D21S11, D7S820, CSF1PO, D5S818, D3S1358, TH01, D13S317, D16S539, D2S1338, TPOX, D19S433, vWA, D18S51, FGA) were determined for a sample of 494 unrelated individuals undergoing kinship analysis and molecular cytogenetic testing from the population of the city of Campos dos Goytacazes, Northern State of Rio de Janeiro, Brazil. The loci with the highest polymorphism information content were D18S51 (0.874), D2S1338 (0.853), FGA (0.852), D21S11 (0.838). The combined power of discrimination and the combined power of exclusion were 0.999999999999999 and 0.999526684, respectively. At the available common loci CSF1PO, TH01, TPOX, vWA, D16S539, D7S820 and D13S317, allele frequencies were compared with population databases from State of Alagoas, State of Amazonas, State of São Paulo (Brazilian mulattoes, descendants of Europeans, Africans or Asians), State of Mato Grosso do Sul and State of Rio de Janeiro. No significant distances were observed. The interpopulation genetic distance (Fst coefficients) to the present database, ranged 0.0022 (p=0.446) (Northern State Rio de Janeiro-State of São Paulo European-descendants) to 0.0138 (p=0.993) (Northern State Rio de Janeiro-State of São Paulo Asian-descendants). The Asian-descendants Brazilians are the least admixed. All other groups are admixed as one unique population.
对来自巴西里约热内卢州北部城市坎波斯·多斯·戈伊塔斯的 494 名无关个体的亲缘关系分析和分子细胞遗传学检测样本,确定了 15 个常染色体短串联重复(STR)常染色体标记物(D8S1179、D21S11、D7S820、CSF1PO、D5S818、D3S1358、TH01、D13S317、D16S539、D2S1338、TPOX、D19S433、vWA、D18S51、FGA)的等位基因频率、亲子关系和法医参数。多态信息含量最高的基因座是 D18S51(0.874)、D2S1338(0.853)、FGA(0.852)、D21S11(0.838)。鉴别力综合指数和排除力综合指数分别为 0.999999999999999 和 0.999526684。在可用的常见基因座 CSF1PO、TH01、TPOX、vWA、D16S539、D7S820 和 D13S317 中,等位基因频率与来自阿拉戈斯州、亚马逊州、圣保罗州(巴西黑白混血儿,欧洲、非洲或亚洲后裔)、南马托格罗索州和里约热内卢州的人群数据库进行了比较。未观察到显著的距离。与本数据库的种群遗传距离(Fst 系数)范围为 0.0022(p=0.446)(里约热内卢州北部-圣保罗州欧洲后裔)至 0.0138(p=0.993)(里约热内卢州北部-圣保罗州亚洲后裔)。亚洲后裔巴西人是最少混合的。所有其他群体都是作为一个独特的混合群体。