Institute of Health and Society, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
Arch Dis Child. 2010 Mar;95(3):203-8. doi: 10.1136/adc.2009.165530. Epub 2009 Nov 29.
Tonsillectomies are frequently performed, yet variations exist in tonsillectomy rates. Clinicians use guidelines, but complex psychosocial influences on childhood tonsillectomy include anecdotal evidence of parental enthusiasm. Studies indicate that undergoing preferred treatment improves outcome. Despite the enthusiasm with which tonsillectomy is offered and sought, there is little evidence of efficacy. This resulted in a randomised controlled trial to evaluate the cost-effectiveness of (adeno)tonsillectomy in children with recurrent sore throats.
To compare characteristics of children entering the randomised trial with those recruited to a parallel, non-randomised study, to establish trends in referral and patient preferences for treatment.
Baseline data from a randomised controlled trial with parallel non-randomised preference study, comparing surgical intervention with medical treatment in children aged 4-15 years with recurrent sore throat referred to five secondary care otolaryngology departments located in the north of England or west central Scotland.
Centres assessed 1546 children; 21% were not eligible for tonsillectomy. Among older children (8-15 years), girls were significantly more likely to be referred to secondary care. Of 1015 eligible children, 268 (28.2%) agreed to be randomised, while 461 (45.4%) agreed to the parallel, non-randomised preference study, with a strong preference for tonsillectomy. Participants reporting that progress at school had been impeded or with more experience of persistent sore throat were more likely to seek tonsillectomy. Referred boys were more likely than girls to opt for medical treatment. Socio-economic data showed no effect.
Preference for tonsillectomy reflects educational impact and recent experience, rather than age or socio-economic status.
扁桃体切除术经常进行,但扁桃体切除术的比率存在差异。临床医生使用指南,但儿童扁桃体切除术的复杂社会心理影响包括家长热情的传闻证据。研究表明,接受首选治疗可改善结果。尽管扁桃体切除术的提供和寻求热情很高,但几乎没有疗效证据。这导致了一项随机对照试验,以评估(腺样)扁桃体切除术在复发性咽痛儿童中的成本效益。
比较进入随机试验的儿童的特征与平行非随机研究中招募的儿童的特征,以确定转诊趋势和患者对治疗的偏好。
一项随机对照试验与平行非随机偏好研究的基线数据,比较手术干预与医学治疗在英格兰北部或苏格兰中西部五个二级护理耳鼻喉科部门转诊的 4-15 岁复发性咽痛儿童。
中心评估了 1546 名儿童;21%不符合扁桃体切除术条件。在年龄较大的儿童(8-15 岁)中,女孩更有可能被转介到二级护理。在 1015 名合格的儿童中,有 268 名(28.2%)同意随机分组,而 461 名(45.4%)同意平行的非随机偏好研究,强烈倾向于扁桃体切除术。报告学业受到阻碍或持续性咽痛经历较多的参与者更倾向于进行扁桃体切除术。被转诊的男孩比女孩更倾向于选择药物治疗。社会经济数据没有显示出影响。
对扁桃体切除术的偏好反映了教育影响和近期的经验,而不是年龄或社会经济地位。