McAlindon T E, Watt I, McCrae F, Goddard P, Dieppe P A
Rheumatology Unit, Bristol Royal Infirmary.
Ann Rheum Dis. 1991 Jan;50(1):14-9. doi: 10.1136/ard.50.1.14.
Twelve knees with a range of severity of knee osteoarthritis were assessed by magnetic resonance imaging (MRI) and technetium-99m labelled hydroxymethylene diphosphonate scintigraphy. Five magnetic resonance pulse sequences were evaluated. Proton density (TR = 1000, TE = 26 ms) and STIR (TR = 1500, TI = 100, TE = 30 ms) were chosen for further use. Abnormalities shown by MRI included joint effusions, meniscal disruption, hyaline cartilage thinning, subchondral signal changes, pseudocysts, and heterogeneity of signal from osteophytes. Certain MRI and scintigraphic appearances correlated: (a) 'hyperintense osteophytosis' and ipsilateral 'tramline' scintigraphic uptake, suggesting increased fat content in 'active' osteophytes; (b) subchondral signal change and 'extended' pattern, possibly reflecting inflammation, synovial leak, or fibrovascular repair; (c) patellofemoral joint signal changes and patellar isotope uptake.
通过磁共振成像（MRI）和锝-99m标记的羟亚甲基二膦酸盐闪烁扫描术对12个具有不同严重程度膝关节骨关节炎的膝盖进行了评估。对五种磁共振脉冲序列进行了评估。选择质子密度（TR = 1000，TE = 26毫秒）和短TI反转恢复序列（STIR，TR = 1500，TI = 100，TE = 30毫秒）以供进一步使用。MRI显示的异常包括关节积液、半月板破裂、透明软骨变薄、软骨下信号改变、假囊肿以及骨赘信号的不均匀性。某些MRI和闪烁扫描表现存在相关性：（a）“高信号骨赘形成”和同侧“轨道样”闪烁扫描摄取，提示“活跃”骨赘中脂肪含量增加；（b）软骨下信号改变和“扩展”模式，可能反映炎症、滑膜渗漏或纤维血管修复；（c）髌股关节信号改变和髌骨同位素摄取。
