Department of Behavioral Pediatric Dentistry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Okayama-shi, Okayama 700-8525, Japan.
J Dent Res. 2010 Jan;89(1):56-60. doi: 10.1177/0022034509352958.
An important caries prevention strategy for children includes measures to interfere with transmission of mutans streptococci (MS). This study confirmed the effectiveness of maternal early exposure to xylitol chewing gum on mother-child transmission of MS. After screening, 107 pregnant women with high salivary MS were randomized into two groups: xylitol gum (Xylitol; n = 56) and no gum (Control; n = 51) groups. Maternal chewing started at the sixth month of pregnancy and terminated 13 months later in the Xylitol group. Outcome measures were the presence of MS in saliva or plaque of the children until age 24 months. The Xylitol-group children were significantly less likely to show MS colonization than Control-group children aged 9-24 months. The Control-group children acquired MS 8.8 months earlier than those in the Xylitol group, suggesting that maternal xylitol gum chewing in Japan shows beneficial effects similar to those demonstrated in Nordic countries.
对于儿童来说，一个重要的龋齿预防策略包括采取措施来干扰变形链球菌（MS）的传播。本研究证实了母亲早期咀嚼木糖醇口香糖对母婴 MS 传播的有效性。经过筛选，107 名唾液中 MS 含量高的孕妇被随机分为两组：木糖醇口香糖组（Xylitol；n = 56）和无口香糖组（Control；n = 51）。母亲从怀孕第六个月开始咀嚼，并在 Xylitol 组 13 个月后结束。结果测量为儿童在 24 个月前唾液或菌斑中是否存在 MS。与 9-24 个月龄的对照组儿童相比，Xylitol 组儿童 MS 定植的可能性明显较低。对照组儿童获得 MS 的时间比 Xylitol 组早 8.8 个月，这表明日本母亲咀嚼木糖醇口香糖的效果与北欧国家的研究结果相似。
