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非心胸手术后心房颤动的发生率及预测因素。

The incidence and predictors of postoperative atrial fibrillation after noncardiothoracic surgery.

机构信息

Division of Cardiology, Cardiac and Vascular Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Korean Circ J. 2009 Mar;39(3):100-4. doi: 10.4070/kcj.2009.39.3.100. Epub 2009 Mar 25.

Abstract

BACKGROUND AND OBJECTIVES

The incidence of postoperative atrial fibrillation after noncardiothoracic surgery is known to be very rare; there have been few prior studies on this topic. We evaluated the incidence, predictors, and prognosis of atrial fibrillation after noncardiothoracic surgery.

SUBJECTS AND METHODS

Patients who underwent noncardiothoracic surgery at our medical center under general anesthesia were enrolled. We reviewed medical records retrospectively and evaluated whether the atrial fibrillation developed postoperatively or was pre-existing. Patients who had a previous history of atrial fibrillation or atrial fibrillation on the pre-operative electrocardiogram were excluded.

RESULTS

Between January 2005 and December 2006, 7,756 patients (mean age: 69 years, male: 46%) underwent noncardiothoracic surgery in Samsung Medical Center and 30 patients (0.39%) were diagnosed with newly-developed atrial fibrillation. Patients who developed atrial fibrillation were significantly older and had significantly lower body mass indexes. Newly-developed atrial fibrillation was detected in 0.53% of the male patients and 0.26% of the female patients. The incidence of postoperative atrial fibrillation after an emergency operation was more frequent than that of elective operations (p<0.001). According to the multivariate analysis, age and emergency operations were independent predictors for new onset atrial fibrillation after noncardiothoracic surgery. Postoperative atrial fibrillation developed after a median of 2 days after the noncardiothoracic surgery and was associated with a longer hospitalization and increased in-hospital mortality. Four (13.3%) patients died and the causes of death were non-cardiovascular events such as pneumonia or hemorrhage.

CONCLUSION

Postoperative atrial fibrillation after noncardiothoracic surgery is a rare complication and is associated with older age and emergency operations. Patients who develop atrial fibrillation have longer hospitalizations and higher in-hospital mortality rates.

摘要

背景与目的

非心胸手术术后心房颤动的发生率已知非常低;关于这个主题的研究很少。我们评估了非心胸手术后心房颤动的发生率、预测因素和预后。

对象与方法

我们纳入了在我们医疗中心接受全身麻醉下非心胸手术的患者。我们回顾性地审查了病历,并评估了心房颤动是在术后发生还是术前存在。排除了有既往心房颤动史或术前心电图上有心房颤动的患者。

结果

在 2005 年 1 月至 2006 年 12 月期间,三星医疗中心有 7756 例(平均年龄:69 岁,男性:46%)患者接受了非心胸手术,有 30 例(0.39%)患者被诊断为新发心房颤动。发生心房颤动的患者明显更年长,体重指数明显更低。新发心房颤动在男性患者中的发生率为 0.53%,女性患者中的发生率为 0.26%。急诊手术后心房颤动的发生率高于择期手术(p<0.001)。根据多变量分析,年龄和急诊手术是非心胸手术后新发心房颤动的独立预测因素。非心胸手术后中位数 2 天后出现心房颤动,并与住院时间延长和住院死亡率增加相关。有 4 例(13.3%)患者死亡,死因是非心血管事件,如肺炎或出血。

结论

非心胸手术后的心房颤动是一种罕见的并发症,与年龄较大和急诊手术有关。发生心房颤动的患者住院时间更长,住院死亡率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec80/2771806/3690f57a8f72/kcj-39-100-g001.jpg

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