Department of Otolaryngology-HNS, Collage of Medicine, The Catholic University of Korea, Seoul, Korea.
J Korean Med Sci. 2009 Dec;24(6):1227-9. doi: 10.3346/jkms.2009.24.6.1227. Epub 2009 Nov 9.
We report a patient with an isolated metastasis to the internal auditory canal (IAC) of bronchogenic adenocarcinoma. A 58-yr-old man who had received 6-cycle of chemotherapy under diagnosis of non-small cell lung carcinoma (T4N2M0) two years ago was referred to our department with vertigo, right-sided facial paralysis and right-sided hearing loss. A provisional diagnosis of vestibular schwannoma or meningioma involving right IAC was made from magnetic resonance imaging. The patient underwent a translabyrinthine removal of the tumor. Histopathological study of the resected lesion showed a poorly differentiated adenocarcinoma compatible with bronchogenic origin. The patient died 9 months after surgery from extensive brain metastasis despite postoperative radiation therapy. In patients with a previous history of treatment of malignancy elsewhere in the body, the possibility of IAC metastasis must be considered when an IAC lesion is detected.
我们报告一例支气管腺癌孤立性内听道（IAC）转移。一名 58 岁男性，两年前被诊断为非小细胞肺癌（T4N2M0），接受了 6 个周期的化疗，因眩晕、右侧面瘫和右侧听力损失被转诊至我科。从磁共振成像来看，初步诊断为右侧 IAC 的前庭神经鞘瘤或脑膜瘤。患者接受了经迷路肿瘤切除术。切除病变的组织病理学研究显示为低分化腺癌，符合支气管起源。尽管术后进行了放疗，但患者在手术后 9 个月死于广泛脑转移。对于有其他部位恶性肿瘤既往治疗史的患者，当发现 IAC 病变时，必须考虑 IAC 转移的可能性。
