Kamischke Axel, Cordes Tim, Nieschlag Eberhard
Abteilung für Andrologie der Klinik für Frauenheilkunde und Geburthilfe, Campus Lübeck des Universitätsklinikums Schleswig-Holstein, Lübeck. Axel.Kamischke@@uk-sh.de
Ther Umsch. 2009 Dec;66(12):789-95. doi: 10.1024/0040-5930.66.12.789.
Male infertility is frequently involved in the couples infertility and therefore the diagnostic work up of the couple should always involve gynaecologists and andrologists. The main task of the interdisciplinary diagnostic work up is the direction of the couple to potential treatments, bearing in mind that spontaneous pregnancies occur frequently in infertile couples. Well established pathways for the male diagnostic work up in infertility exist only marginally. A minimal andrological evaluation should be performed at least in all infertile men after one year of unsuccessful unprotected intercourse or earlier if established male or female risk factors are present. Components of the minimal evaluation of the male partner couple should include at least a reproductive history and two semen analyses according to WHO standards. An evaluation by an andrologist should be done as routine procedure. However, a full andrological evaluation is especially important if the initial evaluation demonstrates an abnormal male reproductive history or an abnormal semen analysis. Further evaluation of the male partner should also be considered in couples with unexplained infertility and in couples in whom there is a treated female factor and persistent infertility. In addition to the requirements of a minimal evaluation, a full evaluation for male infertility should include in addition at least a physical and genital examination. Based on the results of the andrological evaluation, the physician may recommend additional evaluations. These additional evaluations may include an endocrine evaluation, ultrasonography of the scrotal content and/or prostate and seminal vesicles, genetic screening and the conductance of a diagnostic/therapeutic testicular biopsy. Finally the diagnostic work up of the male infertile patient will lead to a solid dia-gnosis on which the subsequent therapeutic procedures must be based.
男性不育在夫妻不育中经常出现,因此对夫妻的诊断检查应始终包括妇科医生和男科医生。跨学科诊断检查的主要任务是指导夫妻进行潜在的治疗,同时要记住,不育夫妻中经常会出现自然怀孕的情况。目前几乎没有完善的男性不育诊断检查途径。至少在所有未采取保护措施的性交一年未成功受孕的不育男性中,或者如果存在已确定的男性或女性风险因素则更早进行,应进行最低限度的男科评估。男性伴侣最低限度评估的组成部分应至少包括生殖史和根据世界卫生组织标准进行的两次精液分析。应由男科医生进行评估作为常规程序。然而,如果初始评估显示男性生殖史异常或精液分析异常,全面的男科评估尤为重要。对于不明原因不育的夫妻以及女性因素已治疗但仍持续不育的夫妻,也应考虑对男性伴侣进行进一步评估。除了最低限度评估的要求外,男性不育的全面评估还应至少包括体格检查和生殖器检查。根据男科评估的结果,医生可能会建议进行其他评估。这些额外的评估可能包括内分泌评估、阴囊内容物和/或前列腺及精囊的超声检查、基因筛查以及诊断性/治疗性睾丸活检。最后,男性不育患者的诊断检查将得出一个可靠的诊断结果,后续的治疗程序必须以此为依据。