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Going viral: fusiform vertebrobasilar and internal carotid aneurysms with varicella angiitis and common variable immunodeficiency.

作者信息

Daugherty Wilson P, Clarke Michelle J, Cloft Harry J, Lanzino Giuseppe L

机构信息

Department of Neurosurgery, Mayo Clinic, 200 1st Street Southwest, Rochester, Minnesota 55905, USA.

出版信息

J Neurosurg Pediatr. 2009 Dec;4(6):528-31. doi: 10.3171/2009.7.PEDS09107.

DOI:10.3171/2009.7.PEDS09107
PMID:19951038
Abstract

Intracranial aneurysms in the pediatric population are relatively rare entities. Immunocompromised patients (often from HIV/AIDS or pharmacological immunosuppression) represent a significant fraction of children with cerebral aneurysms. One proposed mechanism of aneurysm formation in these patients is from direct infection of the affected arteries. In this study, the authors report on a case of a 14-year-old girl with common variable immunodeficiency with T-cell dysfunction and a CSF polymerase chain reaction test positive for varicella-zoster virus who underwent evaluation for carotid and basilar artery fusiform aneurysms.

摘要

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引用本文的文献

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Peripheral B Cell Deficiency and Predisposition to Viral Infections: The Paradigm of Immune Deficiencies.外周 B 细胞缺陷与病毒感染易感性:免疫缺陷的范例。
Front Immunol. 2021 Aug 30;12:731643. doi: 10.3389/fimmu.2021.731643. eCollection 2021.
2
Considerations on the Relevance of Cerebral Fusiform Aneurysms Observed During HIV Infection.关于HIV感染期间观察到的大脑梭形动脉瘤相关性的思考。
Clin Neuroradiol. 2018 Sep;28(3):357-365. doi: 10.1007/s00062-017-0581-0. Epub 2017 Apr 4.
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Neurologic Complications of Common Variable Immunodeficiency.
常见可变免疫缺陷的神经系统并发症
J Clin Immunol. 2016 Nov;36(8):793-800. doi: 10.1007/s10875-016-0336-8. Epub 2016 Oct 4.
4
Diffuse idiopathic intracranial fusiform aneurysm development. Case report and literature review.弥漫性特发性颅内梭形动脉瘤的发生。病例报告及文献综述。
Surg Neurol Int. 2014 Jul 11;5:107. doi: 10.4103/2152-7806.136702. eCollection 2014.