Sim Welkee, Gonski Peter N
Sutherland Hospital, Kingsway, Caringbah, New South Wales, Australia.
Australas J Ageing. 2009 Dec;28(4):194-7. doi: 10.1111/j.1741-6612.2009.00377.x.
To assess the outcomes of patients with acute proximal hip fractures who were taking Clopidogrel.
A retrospective study of 135 patients with proximal hip fractures. Demographic data and clinical outcomes were collected via review of hospital medical records.
21 patients taking Clopidogrel on admission were compared with 114 patients not on Clopidogrel. The groups were similar in their baseline characteristics. Postoperative haemoglobin and wound haematoma, hospital length of stay and death rate were similar in both groups even when the patients on Clopidogrel were operated on within 2 days of fracture. Days to surgery were longer in the Clopidogrel group than the control group (3.5 vs 0.9).
This study demonstrated that patients on Clopidogrel do not have a worse outcome than those who were not taking the medication. We feel that it is safe to perform surgery as soon as possible.
评估服用氯吡格雷的急性近端髋部骨折患者的治疗结果。
对135例近端髋部骨折患者进行回顾性研究。通过查阅医院病历收集人口统计学数据和临床结果。
将入院时服用氯吡格雷的21例患者与未服用氯吡格雷的114例患者进行比较。两组的基线特征相似。即使服用氯吡格雷的患者在骨折后2天内接受手术，两组的术后血红蛋白和伤口血肿、住院时间和死亡率也相似。氯吡格雷组的手术天数比对照组更长（3.5天对0.9天）。
本研究表明，服用氯吡格雷的患者的治疗结果并不比未服用该药物的患者差。我们认为尽快进行手术是安全的。
