作为T淋巴细胞的生与死：从免疫保护到HIV发病机制
Life and death as a T lymphocyte: from immune protection to HIV pathogenesis.
作者信息
Vrisekoop Nienke, Mandl Judith N, Germain Ronald N
机构信息
Lymphocyte Biology Section, Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 10 Center Dr MSC-1892, Bethesda, MD, USA.
出版信息
J Biol. 2009;8(10):91. doi: 10.1186/jbiol198.
Abstract
Detailed analysis of T cell dynamics in humans is challenging and mouse models can be important tools for characterizing T cell dynamic processes. In a paper just published in Journal of Biology, Marques et al. suggest that a mouse model with its activated CD4(+) T cells are deleted has relevance for HIV infection.
摘要
对人类T细胞动力学进行详细分析具有挑战性，而小鼠模型可能是表征T细胞动态过程的重要工具。在刚发表于《生物学杂志》的一篇论文中，马克斯等人指出，一种其活化的CD4(+) T细胞被删除的小鼠模型与HIV感染相关。
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