Krokowski Manuela, Hoch Josef, Feller Alfred C, Bernd Heinz-Wolfram, Thorns Christoph, Krueger Stefan
Department of Pathology, University Hospital of Schleswig-Holstein, Campus Luebeck, Germany.
Dermatol Online J. 2009 Oct 15;15(10):4.
Basal cell carcinoma (BCC), the most common cutaneous malignant tumor, may display neuroendocrine differentiation in very rare instances. We here describe a case of a BCC with neuroendocrine differentiation that arose in a scar resulting from a trauma 75 years earlier. Neuroendocrine differentiation was proven by immunohistochemistry and electron microscopy. The simultaneous occurrence of BCC development in a scar and neuroendocrine differentiation is quite rare.
基底细胞癌（BCC）是最常见的皮肤恶性肿瘤，在极少数情况下可能表现出神经内分泌分化。我们在此描述一例具有神经内分泌分化的基底细胞癌病例，该病例发生于75年前外伤形成的瘢痕处。免疫组织化学和电子显微镜检查证实了神经内分泌分化。瘢痕处同时发生基底细胞癌并伴有神经内分泌分化的情况极为罕见。
