Feramisco Jamison D, Fournier John B, Zedek Daniel C, Venna Suraj S
Department of Dermatology, University of California, San Francisco, San Francisco, California, USA.
Dermatol Online J. 2009 Oct 15;15(10):14.
Angiokeratomas are benign proliferations of dilated thin-walled blood vessels in the upper dermis with overlying epidermal hyperkeratosis. There are several clinical variants of angiokeratomas: 1. Fordyce: smooth reddish-purple papules on scrotum or vulva; 2. Mibelli: hyperkeratotic papules on fingers or toes, solitary, multiple, or circumscriptum (grouped papules usually on an extremity); 4. angiokeratoma corporis diffusum, widespread papules that are a manifestation of one of several inherited lysozomal storage diseases. Herein, we report a rare case of multiple angiokeratomas of Fordyce on the corona of the glans penis.
血管角化瘤是真皮上部扩张的薄壁血管的良性增生，伴有表皮角化过度。血管角化瘤有几种临床变体：1. 福代斯血管角化瘤：阴囊或外阴出现光滑的红紫色丘疹；2. 米贝利血管角化瘤：手指或脚趾上的角化过度丘疹，可为单个、多个或环状（通常在肢体上成群分布的丘疹）；4. 弥漫性躯体血管角化瘤，广泛分布的丘疹，是几种遗传性溶酶体贮积病之一的表现。在此，我们报告一例罕见的阴茎头冠状沟福代斯多发性血管角化瘤病例。
