Wolfsen Herbert C
Division of Gastroenterology and Hepatology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.
Gastrointest Endosc Clin N Am. 2010 Jan;20(1):1-10, v. doi: 10.1016/j.giec.2009.07.006.
This introductory article summarizes decades of research from many dedicated gastrointestinal endoscopists. It provides a background to Barrett esophagus (BE), exploring the risk of progression to dysplasia and esophageal adenocarcinoma. Two premalignant conditions, BE and colon adenoma, are compared, including their progression to esophageal adenocarcinoma and colon and rectal carcinoma, respectively. A comparison of the risks of surgical treatment and post-surgical complications of these cancers and of the strikingly different paradigms for their prevention is presented. The article concludes with the rationale for endoscopic treatment of Barrett disease.
这篇介绍性文章总结了许多专注于胃肠内镜检查的医生数十年的研究成果。它为巴雷特食管（BE）提供了背景信息，探讨了其发展为发育异常和食管腺癌的风险。对两种癌前病变——BE和结肠腺瘤进行了比较，包括它们分别发展为食管腺癌以及结肠癌和直肠癌的情况。还对这些癌症手术治疗的风险、术后并发症以及预防它们的截然不同的模式进行了比较。文章最后阐述了对巴雷特病进行内镜治疗的基本原理。
