Columbia University College of Physicians and Surgeons, New York City, NY, USA.
J Trop Pediatr. 2010 Aug;56(4):280-3. doi: 10.1093/tropej/fmp115. Epub 2009 Dec 1.
The evidence behind the World Health Organization guidelines that BCG vaccination should not be used in HIV-infected children is compelling. We report three cases of severe BCG-associated immune reconstitution syndrome in HIV-infected infants and describe measures available in developing countries that prevent inadvertent BCG immunization in these infants.
世界卫生组织指南指出,BCG 疫苗不应用于感染 HIV 的儿童,这一建议背后的证据确凿。我们报告了 3 例 HIV 感染婴儿发生严重 BCG 相关免疫重建综合征的病例,并描述了发展中国家可采取哪些措施防止这些婴儿意外接种 BCG 疫苗。