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Stimulation of a reconstituted, microsomal NADH oxidase system by carboquone, a quinoid anticancer chemical.

作者信息

Tamura Y, Sato S

出版信息

Gan. 1977 Jun;68(3):353-6.

PMID:199521
Abstract

Carboquone was found to greatly stimulate the aerobic NADH oxidation in the presence of both the partially purified NADH-cytochrome b5 reductase and cytochrome b5 prepared from hepatic microsomes by acting as an electron carrier from cytochrome b5 to molecular oxygen. Other quinoid anticancer chemicals, mitomycin-C, adriamycin, and daunomycin practically failed to do so.

摘要

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