一种对抗华法林抵抗的算法。
An algorithm for managing warfarin resistance.
机构信息
Department of Cardiovascular Medicine, Section of Vascular Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.
出版信息
Cleve Clin J Med. 2009 Dec;76(12):724-30. doi: 10.3949/ccjm.76a.09062.
Some patients need higher-than-expected doses of warfarin (Coumadin) to get their international normalized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood. This review offers an algorithm for the evaluation of patients with suspected warfarin resistance.
有些患者需要高于预期剂量的华法林（Coumadin）才能使国际标准化比值（INR）达到治疗范围。华法林抵抗的原因可能是获得性的（例如，依从性差、药物相互作用、饮食相互作用）或遗传性的，但华法林抵抗的遗传机制尚不清楚。本文提供了一个用于评估疑似华法林抵抗患者的算法。
Zotero 插件