Bruges, Belgium; and Nijmegen, The Netherlands From the Bruges Cleft and Craniofacial Center, General Hospital St. Jan, and the Department of Orthodontics and Oral Biology and the Cleft Palate Craniofacial Center, Radboud University Nijmegen Medical Center.
Plast Reconstr Surg. 2009 Dec;124(6):2061-2071. doi: 10.1097/PRS.0b013e3181bcf2a4.
The authors performed a critical literature review to find evidence of the long-term stability after early distraction osteogenesis of the mandible in patients with hemifacial microsomia.
The PubMed, Cochrane, MEDLINE, EMBASE, CENTRAL, and CINAHL databases were searched systematically for studies performed between 2002 and 2008. Abstracts from the 89 relevant articles were reviewed for evidence.
Thirteen articles met the inclusion criteria. Data were tabulated with respect to the length of follow-up, number of patients, age group, Pruzansky-Kaban classification of the patients, methods of analysis and validation, and level of evidence. Methods for long-term follow-up studies were not standardized, and no objective studies have been published on stability after growth cessation.
Thus far, no randomized controlled trials on early distraction osteogenesis in hemifacial microsomia patients have been published. The authors conclude that there is a lack of statistical evidence to support the use of early distraction osteogenesis for correcting hemifacial microsomia as a single treatment modality. The results call into question its rationale.
作者进行了一次关键性文献回顾，以寻找在单侧颜面短小症患者中，早期牵张成骨术后长期稳定性的证据。
系统检索了 2002 年至 2008 年期间发表的文献，检索数据库包括 PubMed、Cochrane、MEDLINE、EMBASE、CENTRAL 和 CINAHL。对 89 篇相关文章的摘要进行了评估，以寻找证据。
13 篇文章符合纳入标准。对随访时间、患者人数、年龄组、患者的 Pruzansky-Kaban 分类、分析和验证方法以及证据水平进行了数据制表。长期随访研究的方法没有标准化，而且在生长停止后稳定性方面没有发表过客观的研究。
迄今为止，尚未发表单侧颜面短小症患者早期牵张成骨术的随机对照试验。作者得出的结论是，缺乏统计学证据支持将早期牵张成骨术作为单一治疗方法来矫正单侧颜面短小症。结果对其原理提出了质疑。
