Boston, Mass. From the Division of Plastic Surgery, Brigham and Women's Hospital.
Plast Reconstr Surg. 2009 Dec;124(6 Suppl):e340-e350. doi: 10.1097/PRS.0b013e3181bcf094.
Flap prefabrication and prelamination are two closely related concepts. Clinical applications of flap prefabrication and prelamination are relatively new to the field of reconstructive plastic surgery. Although the two terms are often used interchangeably in the literature, they are two distinctly different techniques. Understanding their differences is helpful in planning reconstructive strategy. They are primarily used in reconstructing complex defects where conventional techniques are not available. Flap prefabrication starts with introduction of a vascular pedicle to a desired donor tissue that on its own does not possess an axial blood supply. After a period of neovascularization of at least 8 weeks, this donor tissue can then be transferred to the recipient defect based on the newly acquired axial vasculature. Flap prelamination, in contrast, begins with building a three-dimensional structure on a reliable vascular bed. This composite structure, once matured in approximately 2 weeks, can then be transferred to the recipient defect. This article describes in detail the principles, steps, variations, and applications of these two techniques.
皮瓣预制和预层合是两个密切相关的概念。皮瓣预制和预层合的临床应用在重建整形外科领域相对较新。尽管这两个术语在文献中经常互换使用，但它们是两种截然不同的技术。了解它们的区别有助于规划重建策略。它们主要用于重建复杂的缺陷，在这些缺陷中，常规技术不可用。皮瓣预制始于将血管蒂引入自身不具有轴状血液供应的所需供体组织。经过至少 8 周的新血管生成后，然后可以根据新获得的轴状血管将该供体组织转移到受区缺陷。相比之下，皮瓣预层合始于在可靠的血管床上构建三维结构。这个复合结构在大约 2 周后成熟后，然后可以转移到受区缺陷。本文详细描述了这两种技术的原理、步骤、变化和应用。
