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纵隔甲状腺肿手术中胸骨切开术需求的术前预测因素。

Preoperative predictors of sternotomy need in mediastinal goiter management.

机构信息

Department of Medical & Surgical Sciences, First Division of General Surgery, University of Brescia, Italy.

出版信息

Head Neck. 2010 Sep;32(9):1131-5. doi: 10.1002/hed.21303.

Abstract

BACKGROUND

The objective of this study was to identify the preoperative risk factors for patients in need of a sternotomy in the management of mediastinal goiters in order to provide better preoperative planning and patient consent.

METHODS

We analyzed 98 patients who underwent surgery for mediastinal goiters (goiters extending below the thoracic inlet > or =3 cm with the neck in hyperextension) between 1995 and 2008. Twelve (12.2%) of the patients required a sternotomy. The patients' features were analyzed by the surgical approach performed. Logistic regression analysis was used to study which variables were influencing the surgical strategy. The receiver operating characteristic (ROC) curves were designed when appropriate.

RESULTS

The analysis disclosed the following risk factors: radiologic extension of mediastinal goiters below the aortic arch (odds ratio [OR] = 32.87; 95% confidence interval [CI] = 4.04-267.12; p < .0001); posterior mediastinum involvement for mediastinal goiters with subaortic extension (OR = 7.2; 95% CI = 1.52-34.14; p = .0244); history of mediastinal goiters before surgery (for mediastinal goiters aged >160 months: OR = 22.8; 95% CI = 5.28-98.53; p < .0001).

CONCLUSIONS

Sternotomy need for mediastinal goiter removal can be predicted; in such cases surgeons should not hesitate to perform it for minimizing complications.

摘要

背景

本研究旨在确定纵隔甲状腺肿患者行胸骨切开术的术前危险因素,以便更好地进行术前规划和获得患者同意。

方法

我们分析了 1995 年至 2008 年间因纵隔甲状腺肿(颈过伸位时甲状腺肿延伸至胸廓入口以下>或=3cm)而行手术治疗的 98 例患者。其中 12 例(12.2%)需要行胸骨切开术。通过所施行的手术方法对患者的特征进行分析。采用 logistic 回归分析研究影响手术策略的变量。在适当情况下设计了受试者工作特征(ROC)曲线。

结果

分析显示以下危险因素与胸骨切开术相关:纵隔甲状腺肿在主动脉弓以下的影像学延伸(比值比[OR] = 32.87;95%置信区间[CI] = 4.04-267.12;p <.0001);主动脉下延伸的纵隔甲状腺肿累及后纵隔(OR = 7.2;95% CI = 1.52-34.14;p =.0244);术前纵隔甲状腺肿病史(对于>160 个月的纵隔甲状腺肿:OR = 22.8;95% CI = 5.28-98.53;p <.0001)。

结论

可以预测纵隔甲状腺肿切除术需要行胸骨切开术的情况;在这种情况下,外科医生应毫不犹豫地进行胸骨切开术,以最大限度地减少并发症。

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