Lyzohub V H, Altunina N V
Lik Sprava. 2009 Jan-Feb(1-2):16-22.
59 patients with bronchial asthma (BA) combined with hypertension have been observed. The authors have studied the level changes of cortisol and sexual hormones. Considerable decrease in level of progesterone and cortisol, and also increase in the level of estradiol have been revealed in the patient's blood. It enhances maintenance and progression of bronchoobstructive a syndrome. The authors have also assessed the dynamics of sexual hormones against antihypertensive therapy of patients with BA. Increase in the level of progesterone against administration of amlodipin has been observed in women and increase in the level of testosterone against administration of of enalapril in men. Obtained data allows to optimize the choice of hypotensive medication in patients with BA combined with hypertension.
观察了59例支气管哮喘（BA）合并高血压患者。作者研究了皮质醇和性激素水平的变化。发现患者血液中孕酮和皮质醇水平显著降低，雌二醇水平升高。这增强了支气管阻塞综合征的维持和进展。作者还评估了BA患者抗高血压治疗中性激素的动态变化。观察到女性服用氨氯地平后孕酮水平升高，男性服用依那普利后睾酮水平升高。获得的数据有助于优化BA合并高血压患者降压药物的选择。
