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[头颈外科与神经外科合作治疗颅底肿瘤的管理]

[Cooperation management by head and neck surgery and neurosurgery for skull base tumors].

作者信息

Wu Yue-huang, Wan Jing-hai, Qi Yong-fa, Xu Zhen-gang, Tang Ping-zhang, Guo Jing

机构信息

Department of Head and Neck Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical University, Beijing 100021, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Jun;44(6):475-9.

PMID:19954018
Abstract

OBJECTIVE

To present the experience and advantage of cooperation management by head and neck surgery and neurosurgery for communicating skull base tumors.

METHODS

A review of 54 communicating skull base tumors (benign tumor 21, malignant tumor 33) cooperation resection by head and neck surgery and neurosurgery from July 2005 to July 2008 in the Cancer Hospital of Chinese Academy of Medical Sciences was presented. The tumor originated in the anterior skull base in 19 cases, originated in the lateral skull base in 12, in the central skull base in 17, and in the posterior skull base in 6.

RESULTS

All procedures were conducted in a single stage by a multidisciplinary team. Total resection of tumor was achieved in 45 cases, and subtotal resection was achieved in 9. There was no operative death. There were 2 cases postoperative hemorrhage. All cases except 3 were followed up with a period of 8 to 43 months (median, 19.1 months for benign tumor and 21.0 months for malignant tumor). Three patients with malignant tumor were lost. Twelve cases of malignant tumor and one case of benign tumor recurred postoperatively. Nine patients with malignant tumor had died (one of these died from heart trouble). Three-year disease-free survival rates and overall survival rates of malignant tumor were 52.7% and 53.0%, respectively.

CONCLUSIONS

It suggested that a special operative team constituted of head and neck surgeon and neurosurgeon may improve the outcome of the difficult skull base tumors.

摘要

目的

介绍头颈外科与神经外科合作管理沟通性颅底肿瘤的经验及优势。

方法

回顾中国医学科学院肿瘤医院2005年7月至2008年7月间头颈外科与神经外科合作切除的54例沟通性颅底肿瘤(良性肿瘤21例,恶性肿瘤33例)。肿瘤起源于前颅底19例,起源于侧颅底12例,起源于中颅底17例,起源于后颅底6例。

结果

所有手术均由多学科团队一期完成。45例实现肿瘤全切,9例次全切除。无手术死亡。术后有2例出血。除3例失访外,其余病例随访8至43个月(中位时间,良性肿瘤19.1个月,恶性肿瘤21.0个月)。3例恶性肿瘤患者失访。12例恶性肿瘤和1例良性肿瘤术后复发。9例恶性肿瘤患者死亡(其中1例死于心脏病)。恶性肿瘤的3年无病生存率和总生存率分别为52.7%和53.0%。

结论

提示由头颈外科医生和神经外科医生组成的特殊手术团队可能改善困难颅底肿瘤的治疗效果。

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Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Jun;44(6):475-9.
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