School of Chemistry, Seoul National University, NS60, Seoul 151-742, Korea.
J Am Chem Soc. 2010 Jan 13;132(1):297-302. doi: 10.1021/ja907491u.
Solvent-inventory experiments on the excited-state proton transfer of a 7-hydroxyquinoline molecule complexed cyclically with two alcohol molecules in the host medium of n-alkane have been carried out with various combinations of alcohols having different proton-donating abilities. Alcohol molecules participating in the hydrogen-bonded chain of the cyclic complex accelerate proton transfer in a concerted fashion by accumulating their proton-donating abilities. The rate-determining deprotonation of the alcohol molecule hydrogen-bonded directly to the imino group of 7-hydroxyquinoline is stimulated by the push-ahead effect of the next alcohol molecule in the hydrogen-bonded chain. Our results provide a clue at the level of molecules on the fundamental mechanistic elucidation of proton transport occurring through a proton wire consisting of diverse amino acids.
溶剂库存实验表明，在正烷烃的主体介质中，与两个醇分子周期性络合的 7-羟基喹啉分子的激发态质子转移，与具有不同供质子能力的各种醇组合进行。参与环状配合物氢键链的醇分子通过积累其供质子能力，以协同方式加速质子转移。直接与 7-羟基喹啉亚氨基键合的醇分子的去质子化速率决定于氢键链中下一醇分子的推动效应。我们的结果为通过由不同氨基酸组成的质子线发生质子传递的基本机理阐明提供了分子水平上的线索。
