具有传统钙离子载体的镁选择性离子通道模拟传感器。
Magnesium-selective ion-channel mimetic sensor with a traditional calcium ionophore.
机构信息
Institute for Chemical Physics, Beijing Institute of Technology, Beijing, China, 100081.
出版信息
Anal Chem. 2010 Jan 1;82(1):436-40. doi: 10.1021/ac901570u.
PMID:19954237
Abstract
A novel magnesium-selective ion-channel mimetic sensor based on a well-known calcium ionophore, ETH 5234, was demonstrated. Due to different stoichiometry of the ionophore with Mg(2+) and Ca(2+), the sensor exhibits high selectivity to Mg(2+) by controlling ionophore concentration on the electrode surface, which allows the measurement of Mg(2+) in a 1 mM Ca(2+) background solution.
摘要
基于一种著名的钙离子载体 ETH 5234，展示了一种新型的镁选择性离子通道模拟传感器。由于离子载体与 Mg(2+)和 Ca(2+)的计量比不同，通过控制电极表面上的离子载体浓度，传感器对 Mg(2+)表现出高选择性，从而可以在 1mM Ca(2+)背景溶液中测量 Mg(2+)。
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