Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland SR2 9HP, UK.
Br J Ophthalmol. 2010 Sep;94(9):1219-25. doi: 10.1136/bjo.2009.170126. Epub 2009 Dec 2.
To assess the effectiveness of treatment to the inner sclerostomy sites at the time of vitrectomy for proliferative diabetic retinopathy (PDR) in reducing the incidence of late recurrent postoperative vitreous cavity haemorrhage (POVCH).
Retrospective study of a consecutive series of 82 eyes undergoing vitrectomy for PDR by a single surgeon treated with either cryotherapy or argon laser directly to the inner sclerostomy site at the completion of surgery (treatment group). These were compared with a previous consecutive series of 82 eyes operated on by the same surgeon who did not have inner sclerostomy site treatment (control group). The occurrence of any POVCH was recorded within the first 6 months of surgery.
The composition of the two groups was similar in terms of age, indication for surgery and a variety of other preoperative factors. There were 64 patients in the control group and 65 in the treatment group. There was a significant reduction in the incidence of late recurrent POVCH in the treatment group. Late recurrent POVCH occurred in 12 (15%) eyes in the control group compared with five (6%) in the treatment group (p=0.03). The number of eyes requiring revision surgery within the first 6 months for late recurrent POVCH was four (5%) in the control group and two (2.5%) in the treatment group (p=0.31).
This study suggests that inner sclerostomy site treatment is effective in reducing the occurrence of recurrent late POVCH in patients undergoing vitrectomy for PDR. A randomised controlled study is needed to clarify this.
评估在增生性糖尿病视网膜病变(PDR)玻璃体切割术中对内直肌巩膜造口部位进行治疗,以减少晚期复发性术后玻璃体积血(POVCH)发生的效果。
对一位医生进行的连续 82 例 PDR 玻璃体切除术的回顾性研究,这些患者中有 41 例在手术结束时对内直肌巩膜造口部位进行冷冻或氩激光治疗(治疗组),而另外 41 例没有进行内直肌巩膜造口部位治疗(对照组)。术后 6 个月内记录任何 POVCH 的发生情况。
两组在年龄、手术指征和其他术前因素方面相似。对照组有 64 例患者,治疗组有 65 例患者。治疗组晚期复发性 POVCH 的发生率明显降低。对照组有 12 只眼(15%)出现晚期复发性 POVCH,而治疗组有 5 只眼(6%)(p=0.03)。对照组中有 4 只眼(5%)需要在术后 6 个月内因晚期复发性 POVCH 进行翻修手术,而治疗组中有 2 只眼(2.5%)(p=0.31)。
本研究表明,在接受 PDR 玻璃体切除术的患者中,对内直肌巩膜造口部位进行治疗可有效减少晚期复发性 POVCH 的发生。需要进行随机对照研究来进一步阐明这一点。