Department of Anesthesiology, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA.
Anesth Analg. 2010 Feb 1;110(2):526-8. doi: 10.1213/ANE.0b013e3181c76be9. Epub 2009 Dec 2.
Herein, we report a patient treated preoperatively with multiple psychiatric medications who developed serotonin syndrome (SS) during the perioperative period. SS was diagnosed using the Hunter Criteria (use of multiple serotonergic drugs preoperatively, hypertonia, and spontaneous clonus) and was presumed to have been triggered by the combination of perioperative and intraoperative serotonergic medications. It is essential that perioperative physicians, especially anesthesiologists, understand the risk factors, clinical scenario, and treatment of SS.
在此，我们报告了一例术前使用多种精神科药物治疗的患者，该患者在围手术期发生了血清素综合征（SS）。SS 的诊断采用 Hunter 标准（术前使用多种 5-羟色胺能药物、张力亢进和自发性阵挛），并推测是由围手术期和术中 5-羟色胺能药物的联合作用引发的。了解 SS 的危险因素、临床情况和治疗方法对围手术期医生，特别是麻醉医生来说至关重要。
