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就业状况与妊娠并发症风险:生育队列研究。

Employment status and the risk of pregnancy complications: the Generation R Study.

机构信息

The Generation R Study Group, Erasmus MC-University Medical Centre Rotterdam, PO Box 2040 (Room Ae-029), 3000 CA Rotterdam, the Netherlands.

出版信息

Occup Environ Med. 2010 Jun;67(6):387-94. doi: 10.1136/oem.2009.046300. Epub 2009 Dec 2.

Abstract

OBJECTIVES

This study explored the relationships of employment status, type of unemployment and number of weekly working hours, with a wide range of pregnancy outcomes.

METHODS

Information on employment characteristics and pregnancy outcomes was available for 6111 pregnant women enrolled in a population-based cohort study in the Netherlands.

RESULTS

After adjustment for confounders, there were no statistically significant differences in risks of pregnancy complications between employed and unemployed women. Among unemployed women, women receiving disability benefit had an increased risk of preterm ruptured membranes (OR 3.16, 95% CI 1.49 to 6.70), elective caesarean section (OR 2.98, 95% CI 1.21 to 7.34) and preterm birth (OR 2.64, 95% CI 1.32 to 5.28) compared to housewives. Offspring of students and women receiving disability benefit had a significantly lower mean birth weight than offspring of housewives (difference: -93, 95% CI -174 to -12; and -97, 95% CI -190 to -5, respectively). In employed women, long working hours (>or=40 h/week) were associated with a decrease of 45 g in offspring's mean birth weight (adjusted analysis; 95% CI -89 to -1) compared with 1-24 h/weekly working hours.

CONCLUSIONS

We found no indications that paid employment during pregnancy effects the health of the mother and child. However, among unemployed and employed women, women receiving disability benefit, students and women with long working hours during pregnancy were at risk for some adverse pregnancy outcomes. More research is needed to replicate these results and explain these findings. Meanwhile, prenatal care providers should be made aware of the risks associated with specific types of unemployment and long working hours.

摘要

目的

本研究探讨了就业状况、失业类型和每周工作时间长短与多种妊娠结局的关系。

方法

荷兰一项基于人群的队列研究纳入了 6111 名孕妇,本研究分析了这些孕妇的就业特征和妊娠结局信息。

结果

调整混杂因素后,与就业女性相比,失业女性发生妊娠并发症的风险无统计学差异。在失业女性中,领取伤残津贴的女性发生胎膜早破(OR=3.16,95%CI:1.49-6.70)、选择性剖宫产(OR=2.98,95%CI:1.21-7.34)和早产(OR=2.64,95%CI:1.32-5.28)的风险增加;与家庭主妇相比,学生和领取伤残津贴女性的新生儿出生体重明显较低(差值分别为-93,95%CI:-174 至-12;-97,95%CI:-190 至-5)。对于就业女性,与每周工作 1-24 小时相比,每周工作时间大于或等于 40 小时与新生儿出生体重均值降低 45 克(校正分析;95%CI:-89 至-1)相关。

结论

本研究未发现妊娠期间有薪就业会影响母婴健康。然而,在失业和就业女性中,领取伤残津贴的女性、学生和妊娠期间工作时间较长的女性发生某些不良妊娠结局的风险增加。需要更多的研究来复制这些结果并解释这些发现。同时,产前保健提供者应了解特定类型的失业和长时间工作相关的风险。

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