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对于所有产前肾积水病例,排尿性膀胱尿道造影是否都有必要?

Is voiding cystourethrogram necessary in all cases of antenatal hydronephrosis?

作者信息

Ansari M S, Ayyildiz Halil Suat, Jayanthi V R

机构信息

Pediatric Urology, Nationwide Children Hospital, Columbus - 432 05, OH, USA.

出版信息

Indian J Urol. 2009 Oct-Dec;25(4):545-6. doi: 10.4103/0970-1591.57911.

DOI:10.4103/0970-1591.57911
PMID:19955688
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2808667/
Abstract

Hydronephrosis is the most common genitourinary anomaly as detected on obstetric ultrasonography and the incidence of associated vesicoureteral reflux is around 10-12%. There is inconsistency in the literature regarding which child should under go a voiding cystourethrogram (VCUG) in cases of antenatal hydronephrosis (AHN). Besides, there is a scarcity of prospective studies to demonstrate the risk of varying degree of AHN, associated reflux and their long-term impact on the kidneys. The present analysis suggests that children with AHN should undergo an ultrasound within the first month of life and further course of action should be decided on the basis of the individual case. Children with persistent moderate to severe AHN should undergo a VCUG and a functional study.

摘要

肾积水是产科超声检查中最常见的泌尿生殖系统异常,伴有膀胱输尿管反流的发生率约为10%-12%。关于产前肾积水(AHN)病例中哪些儿童应接受排尿性膀胱尿道造影(VCUG),文献中存在不一致的观点。此外,缺乏前瞻性研究来证明不同程度的AHN、相关反流的风险及其对肾脏的长期影响。目前的分析表明,AHN患儿应在出生后第一个月内接受超声检查,并应根据个体情况决定进一步的治疗方案。持续性中度至重度AHN患儿应接受VCUG和功能检查。

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1
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Indian J Urol. 2009 Oct-Dec;25(4):545-6. doi: 10.4103/0970-1591.57911.
2
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本文引用的文献

1
Fetal hydronephrosis; prevalence, natural history and postnatal consequences in an unselected population.胎儿肾积水:未选择人群中的患病率、自然病史及出生后后果
Acta Obstet Gynecol Scand. 2007;86(12):1463-6. doi: 10.1080/00016340701714802. Epub 2007 Oct 16.
2
Antenatal hydronephrosis as a predictor of postnatal outcome: a meta-analysis.产前肾积水作为产后结局的预测指标:一项荟萃分析。
Pediatrics. 2006 Aug;118(2):586-93. doi: 10.1542/peds.2006-0120.
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Antenatal hydronephrosis: negative predictive value of normal postnatal ultrasound--a 5-year study.产前肾积水:产后超声检查正常的阴性预测值——一项为期5年的研究
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Pediatr Nephrol. 2003 Dec;18(12):1224-8. doi: 10.1007/s00467-003-1287-x. Epub 2003 Oct 30.
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Long-term followup of prenatally detected severe bilateral newborn hydronephrosis initially managed nonoperatively.产前检测出的严重双侧新生儿肾积水最初采用非手术治疗的长期随访
J Urol. 2002 Sep;168(3):1118-20. doi: 10.1016/S0022-5347(05)64604-6.
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The natural history of neonatal vesicoureteral reflux associated with antenatal hydronephrosis.与产前肾积水相关的新生儿膀胱输尿管反流的自然病史。
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7
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8
Antenatal diagnosis and subsequent management of hydronephrosis.产前肾积水的诊断及后续处理
J Urol. 1993 Apr;149(4):693-8. doi: 10.1016/s0022-5347(17)36185-2.
9
Incidental vesicoureteral reflux in neonates with antenatally detected hydronephrosis and other renal abnormalities.产前检测出肾积水及其他肾脏异常的新生儿中的偶然发现的膀胱输尿管反流。
Radiology. 1993 Apr;187(1):157-60. doi: 10.1148/radiology.187.1.8451404.
10
Congenital renal damage associated with primary vesicoureteral reflux detected prenatally in male infants.产前在男婴中检测到的与原发性膀胱输尿管反流相关的先天性肾损伤。
J Pediatr. 1994 May;124(5 Pt 1):726-30. doi: 10.1016/s0022-3476(05)81362-9.