Davies Shelley
Medical Information Department, Thomson Reuters, Barcelona, Spain.
Drugs Today (Barc). 2009 Sep;45(9):663-8.
Restless legs syndrome (RLS) is a neurological disorder related to abnormal and unpleasant sensations and movements in the legs. It usually occurs at nighttime and thus has a detrimental impact on the ability to sleep, leading to poor patient quality of life. UCB has been developing rotigotine transdermal patch system (Neupro; SPM-962) as a treatment for RLS. This system is designed to replace levels of dopamine in the body via once-daily application of the patch, in a bid to restore proper motor functioning. The rotigotine patch has been authorized for the treatment of RLS since August 2008.
不宁腿综合征(RLS)是一种神经系统疾病,与腿部异常且不适的感觉及运动有关。它通常在夜间发作,因此对睡眠能力有不利影响,导致患者生活质量低下。优时比(UCB)一直在研发罗替戈汀透皮贴剂系统(Neupro;SPM - 962)用于治疗不宁腿综合征。该系统旨在通过每日一次贴敷贴剂来补充体内多巴胺水平,以恢复正常的运动功能。自2008年8月起,罗替戈汀贴剂已获批准用于治疗不宁腿综合征。