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[湖南省美沙酮维持治疗患者的留存时间及相关影响因素研究]

[Study on the time of retention and related influencing factors of patients receiving methadone maintenance treatment in Hunan province].

作者信息

Li Xing-Li, Tan Hong-Zhuan, Sun Zhen-Qiu, Zhang Heng, Chen Meng-Shi, Ou Qiu-Ying

机构信息

School of Public Health of Central South University, Changsha, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Jul;30(7):672-5.

Abstract

OBJECTIVE

to explore the current situation and related influencing factors on the retention time of patients receiving methadone maintenance treatment (MMT).

METHODS

Information on basic situation and daily treatment of the patients were collected from the 7 MMT clinics opened in the pro-two batch in Hunan province. Retention rate and influencing factors were analyzed.

RESULTS

(1) The retention rates after 6 and 12 months of MMT became 72.06% and 49.65% respectively. (2) The retention rates of high-dosage group and low-dosage group were 85.03% and 68.03% after 6 months on MMT program while became 60.48% and 46.28% after 12 months of MMT respectively. (3) The mean retention time of HIV+ patients and HIV patients were 9.46 months and 8.62 months respectively during the 12 months follow-up observation, showing a significant difference. (4) Patients who took large dose methadone, did not share needles, at older age or HIV+, were prone to keep MMT at a long period.

CONCLUSION

The retention rates for 6 months and 12 months in the MMT program in Hunan province were similar to the national data. Dose, type of drug abuse, age and HIV status were related to the period of retention.

摘要

目的

探讨接受美沙酮维持治疗(MMT)患者的留存时间现状及相关影响因素。

方法

收集湖南省第二批开设的7家MMT门诊患者的基本情况及日常治疗信息,分析留存率及影响因素。

结果

(1)MMT治疗6个月和12个月后的留存率分别为72.06%和49.65%。(2)MMT治疗6个月时,高剂量组和低剂量组的留存率分别为85.03%和68.03%,MMT治疗12个月后分别为60.48%和46.28%。(3)在12个月的随访观察中,HIV阳性患者和HIV阴性患者的平均留存时间分别为9.46个月和8.62个月,差异有统计学意义。(4)服用大剂量美沙酮、不共用针具、年龄较大或HIV阳性的患者更容易长期坚持MMT治疗。

结论

湖南省MMT项目6个月和12个月的留存率与全国数据相似。剂量、药物滥用类型、年龄和HIV感染状况与留存时间有关。

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