Doroshenko B H, Saliuta M Iu, Nazar P S, Kotko M D, Karpenko O I, Bezuhlova S V
Lik Sprava. 2009 Apr-Jun(3-4):9-12.
For the first time it is established that patients with acute virus myocarditis (AVM) at all stages of severity of clinical course of the disease have changes in indicators of fibrinogens, soluble complexes of monomeric fibrin, products of its degradation, activated plasminogen, time recalcification of blood plasma to blood heparin, fibrinolytic activity of plasma, spontaneous fibrinolysis, time of lysis of euglobulin clot, blood heparin, antithrombin III, platelets. It testifies to suppression of fibrinolysis processes which expressiveness statistically reliably correlates with degree of severity of clinical course of AVM. Application of medicamentous correction is necessary for prevention of the development of disseminated intravascular blood coagulation syndrome.
首次确定,在急性病毒性心肌炎(AVM)患者疾病临床过程的所有严重程度阶段,其纤维蛋白原、单体纤维蛋白可溶性复合物、其降解产物、活化纤溶酶原、血浆复钙时间、血浆纤溶活性、自发纤溶、优球蛋白凝块溶解时间、血液肝素、抗凝血酶III、血小板等指标均有变化。这证明纤溶过程受到抑制,其表达程度与AVM临床过程的严重程度在统计学上具有可靠的相关性。为预防弥散性血管内凝血综合征的发展,进行药物纠正很有必要。