Fong Jim C W, Michael Philip, Raut Vivek
New Cross Hospital, Wolverhampton, UK.
Acta Otolaryngol. 2010 May;130(5):554-8. doi: 10.3109/00016480903338131.
In this comparative series, hearing results were superior with titanium compared with autograft ossiculoplasty in the absence of a stapes superstructure. However, in the presence of a stapes superstructure, titanium ossiculoplasties gave superior results to autografts only when comparing an air-bone gap of < 10 dB.
To compare the hearing outcomes of autograft versus titanium ossiculoplasty at 1 year.
Two consecutive groups of patients with chronic suppurative otitis media with and without cholesteatoma suitable for ossiculoplasty, either primarily or as a staged procedure, were recruited for the study. A total of 52 consecutive patients who underwent an autograft ossiculoplasty were compared with 51 consecutive patients who underwent a titanium ossiculoplasty. Hearing results were statistically compared at 1 year between the two groups using the four frequency average (FFA) of 0.5/1/2/4 kHz and the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) four frequency average of 0.5/1/2/3 kHz. The results were analysed statistically.
A statistically significant number of titanium TORP ossiculoplasties achieved an air-bone gap closure to within < 20 dB compared with the autograft equivalent group (p = 0.039 FFA; p = 0.016 AAO-HNS). The number of titanium PORP ossiculoplasties achieving an air-bone gap closure to within < 10 dB compared with the autograft equivalent group was also statistically significant (p = 0.006 FFA; p = 0.002 AAO-HNS).
在本比较系列研究中，在没有镫骨上部结构的情况下，与自体骨听骨成形术相比，钛质听骨的听力结果更佳。然而，在存在镫骨上部结构的情况下，仅当比较气骨导差<10dB时，钛质听骨成形术的结果才优于自体骨听骨成形术。
比较自体骨与钛质听骨成形术1年后的听力结果。
连续两组适合进行听骨成形术（无论是一期手术还是分期手术）的慢性化脓性中耳炎伴或不伴胆脂瘤患者被纳入研究。将连续52例行自体骨听骨成形术的患者与连续51例行钛质听骨成形术的患者进行比较。使用0.5/1/2/4kHz的四个频率平均值（FFA）和美国耳鼻咽喉-头颈外科学会（AAO-HNS）的0.5/1/2/3kHz四个频率平均值，对两组1年后的听力结果进行统计学比较。对结果进行统计学分析。
与自体骨等效组相比，钛质全听骨重建假体（TORP）听骨成形术实现气骨导差缩小至<20dB的数量具有统计学意义（FFA：p = 0.039；AAO-HNS：p = 0.016）。与自体骨等效组相比，钛质部分听骨重建假体（PORP）听骨成形术实现气骨导差缩小至<10dB的数量也具有统计学意义（FFA：p = 0.006；AAO-HNS：p = 0.002）。
