Transplant Infectious Diseases, University of Alberta, Edmonton, Alberta, Canada.
Am J Transplant. 2010 Jan;10(1):18-25. doi: 10.1111/j.1600-6143.2009.02960.x. Epub 2009 Dec 2.
Novel influenza A/H1N1 virus has caused significant illness worldwide. In response to this global crisis, the American Society of Transplantation (AST) Infectious Diseases Community of Practice and the Transplant Infectious Diseases section of The Transplantation Society (TTS) developed a guidance document for novel H1N1. In this paper, we discuss current guidance for H1N1 as it relates to solid organ transplantation. We include discussion around clinical presentation, diagnosis, therapy and prevention specifically addressing areas such as chemoprophylaxis, immunization and donor-derived infection. Although this document addresses conditions specific to novel H1N1, many principles could be applied to future pandemics. As new information emerges about novel H1N1, updates will be made to the electronic version of the document posted on the websites of the AST and TTS.
新型甲型 H1N1 流感病毒已在全球范围内引发了严重疾病。为应对这一全球危机，美国移植协会（AST）传染病实践社区和移植学会传染病分会（TTS）为新型 H1N1 病毒制定了一份指导文件。在本文中，我们讨论了与实体器官移植相关的当前 H1N1 指导意见。我们讨论了临床特征、诊断、治疗和预防，特别涉及化学预防、免疫接种和供体源性感染等领域。尽管本文件针对新型 H1N1 特定情况，但许多原则也可应用于未来的大流行。随着有关新型 H1N1 的新信息不断出现，AST 和 TTS 网站上发布的文件的电子版将进行更新。
