Department of Biomedical Engineering and Physics, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
J Biomech. 2010 Mar 22;43(5):1007-10. doi: 10.1016/j.jbiomech.2009.11.003. Epub 2009 Dec 2.
Biomechanical models may aid in improving diagnosis and treatment of wrist joint disorders. As input, geometrical information is required for model development. Previous studies acquired some elements of the average wrist joint geometry. However, there is a close geometric functional match between articulating surfaces and ligament geometry. Therefore, biomechanical models need to be fed with the geometric data of individual joints. This study is aimed at acquiring geometric data of cartilage surfaces and ligaments from individual wrist joints by using a cryomicrotome imaging system and the evaluation of inter- and intra-observer variability of the data. The 3D geometry of 30 cartilage surfaces and 15 ligaments in three cadaver wrists was manually detected and quantitatively reconstructed. The inter- and intra-observer variability of the cartilage surface detection was 0.14 and 0.19 mm, respectively. For the position of the radius attachment of the dorsal radiocarpal ligament (DRC), the observer variations were 0.12 and 0.65 mm, for intra-/inter-observer, respectively. For the DRC attachment on the triquetrum, the observer variations were 0.22 and 1.19 mm. Anatomic reconstruction from 3D cryomicrotome images offer a method to obtain unique geometry data of the entire wrist joint for modeling purposes.
生物力学模型可以帮助改善腕关节疾病的诊断和治疗。作为输入，模型开发需要几何信息。以前的研究已经获得了一些平均腕关节几何形状的元素。然而，关节表面和韧带几何形状之间存在紧密的几何功能匹配。因此，生物力学模型需要用个体关节的几何数据进行喂养。本研究旨在通过使用冷冻切片成像系统获取个体腕关节软骨表面和韧带的几何数据，并评估数据的观察者内和观察者间变异性。手动检测了三个尸体腕关节中 30 个软骨表面和 15 个韧带的 3D 几何形状，并进行了定量重建。软骨表面检测的观察者内和观察者间变异性分别为 0.14 和 0.19 毫米。对于背侧桡腕掌侧韧带（DRC）桡骨附着点的位置，观察者间变异性分别为 0.12 和 0.65 毫米，观察者内变异性分别为 0.22 和 1.19 毫米。来自 3D 冷冻切片图像的解剖重建提供了一种方法，可以为建模目的获取整个腕关节的独特几何数据。
