Maréchaux Sylvestre, Terrade Julia, Biausque Frédéric, Lefetz Yann, Deturck Régis, Asseman Philippe, Le Jemtel Thierry H, Ennezat Pierre V
Centre Hospitalier Régional et Universitaire de Lille, Service d'explorations fonctionnelles cardiovasculaires, Lille, France.
Eur J Echocardiogr. 2010 May;11(4):E14. doi: 10.1093/ejechocard/jep203. Epub 2009 Dec 3.
We report here the worsening of functional mitral regurgitation (MR) during dynamic exercise Doppler echocardiography in four female patients with heart failure and preserved ejection fraction. MR worsened concomitantly to an increase in systolic mitral tenting area and in E/E(a) ratio, whereas local left ventricular (LV) remodelling was not substantially aggravated by exercise. We accordingly suggest that exercise-induced increase in LV filling or left atrial pressure that in turn leads to increase in mitral tenting area worsens functional MR during exercise.
我们在此报告4例射血分数保留的心力衰竭女性患者在动态运动多普勒超声心动图检查期间功能性二尖瓣反流（MR）恶化的情况。MR的恶化与收缩期二尖瓣瓣叶膨出面积及E/E(a)比值的增加同时出现，而局部左心室（LV）重构并未因运动而显著加重。因此，我们认为运动引起的左心室充盈或左心房压力增加，进而导致二尖瓣瓣叶膨出面积增加，会使运动期间的功能性MR恶化。
