J Neurol. 2010 Apr;257(4):655-7. doi: 10.1007/s00415-009-5412-z. Epub 2009 Dec 4.
We report a successful treatment with rituximab in a patient with CANOMAD neuropathy resistant to previous therapy. The titers of anti-disialosyl antibodies were decreased 3 months after the beginning of the treatment and the sensory ataxia clearly improved after 9 months of therapy.
我们报告了一例使用利妥昔单抗治疗对既往治疗抵抗的 CANOMAD 神经病患者获得成功的病例。在治疗开始后 3 个月,抗二唾液酸神经节苷脂抗体滴度下降,在治疗 9 个月后,感觉性共济失调明显改善。