Department of Gynecology, Hannover Medical School, Hannover, Germany.
Arch Gynecol Obstet. 2010 Jul;282(1):75-82. doi: 10.1007/s00404-009-1302-y. Epub 2009 Dec 4.
To investigate the quality of life and satisfaction after different operations in patients with breast cancer, which are breast conserving therapy (BCT), mastectomy and reconstruction after breast BCT or mastectomy.
180 patients with breast cancer who were operated from January 2005 to October 2006 were chosen. They presented without local or distant metastasis in this period of time and were asked to complete the EORTC quality of life questionnaire (QLQ-C30), the EORTC breast cancer module questionnaire (QLQ-BR23) and a specific questionnaire regarding satisfaction of postoperative results designed by ourselves.
Of 112 (62.2%) patients who responded there were 76, 20 and 16 patients in the group of BCT, mastectomy and reconstruction, respectively. Compared with the mastectomy group and reconstruction group, the patients in BCT group had better body image (BI) (P = 0.004, P = 0.003), the patients in the group of reconstruction had more financial difficulties (FD) and more future perspective (FP) than the BCT group (P = 0.006, P = 0.039). Compared with the group of mastectomy and reconstruction, the patients in the group of BCT had a better self-assessment of postoperative results (P = 0.001, P < 0.001) and less visible postoperative scars (P = 0.003, P = 0.019). Patients in the reconstruction group thought that the difference in shape of the bilateral breast was more visible than in the BCT group (P = 0.005). Regarding visible differences in size of the breasts and satisfaction with the position and form of nipple-areolar complex, there were no differences between the two groups (P = 0.077, P = 0.272).
Patients with BCT have a better quality of life and higher satisfaction rate with their postoperative breasts compared to patients undergoing mastectomy or reconstructive surgery.
调查保乳治疗（BCT）、乳房切除术和乳房 BCT 或乳房切除术后重建后不同手术方式的乳腺癌患者的生活质量和满意度。
选择 2005 年 1 月至 2006 年 10 月期间接受手术的 180 例乳腺癌患者。这些患者在这段时间内没有局部或远处转移，并被要求完成 EORTC 生活质量问卷（QLQ-C30）、EORTC 乳腺癌模块问卷（QLQ-BR23）以及我们自己设计的关于术后结果满意度的特定问卷。
在 112 名（62.2%）回复的患者中，BCT 组、乳房切除术组和重建组分别有 76、20 和 16 名患者。与乳房切除术组和重建组相比，BCT 组患者的身体形象（BI）更好（P=0.004，P=0.003），重建组患者的经济困难（FD）和未来前景（FP）比 BCT 组更严重（P=0.006，P=0.039）。与乳房切除术和重建组相比，BCT 组患者对术后结果的自我评估更好（P=0.001，P<0.001），术后疤痕更不明显（P=0.003，P=0.019）。重建组患者认为双侧乳房形状差异更明显（P=0.005）。对于乳房大小的可见差异以及对乳头乳晕复合体位置和形态的满意度，两组之间没有差异（P=0.077，P=0.272）。
与接受乳房切除术或重建手术的患者相比，BCT 患者的生活质量更高，对术后乳房的满意度更高。
