Division of Periodontology, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA.
J Periodontol. 2009 Dec;80(12):2073-81. doi: 10.1902/jop.2009.090311.
The gingival cyst of the adult (GCA) is an uncommon developmental cyst of odontogenic origin most frequently seen near mandibular canines and premolars and is routinely treated with excisional biopsy. This article presents a case of a GCA treated with a combined regenerative approach and reviews the GCA literature with an emphasis on the clinical aspects of this lesion.
A 54 year-old man presented for treatment of generalized severe chronic periodontitis. Clinical examination revealed a cystic lesion in the gingiva of the mandibular canine-premolar area. Radiographs revealed a well-defined radiolucency in the coronal one-third of the tooth roots. Surgical enucleation of the lesion revealed root exposure of the second premolar. Because of the anatomy of the lesion-associated defect, regenerative treatment, using a combination of freeze-dried bone allograft and a collagen membrane, was considered the therapeutic approach of choice.
The biopsy revealed histologic features consistent with a GCA. Clinical and radiographic examinations 1 year post-surgery indicated uneventful soft tissue healing and bone fill of the initial defect. The review of the literature revealed only one other case of root exposure associated with GCA and no previous report of regenerative therapy.
In rare instances, a GCA lesion may result in tooth-root exposure. In such cases, a combined regenerative treatment approach may be used to achieve resolution.
成人牙龈囊肿（GCA）是一种源自牙源性的罕见发育性囊肿，最常发生在下颌尖牙和前磨牙附近，通常通过切除活检进行治疗。本文介绍了一例采用联合再生方法治疗的 GCA 病例，并对 GCA 文献进行了回顾，重点介绍了该病变的临床方面。
一名 54 岁男性因广泛严重慢性牙周炎就诊。临床检查显示下颌尖牙-前磨牙区牙龈有囊性病变。X 线片显示牙根冠三分之一处有明确的透光区。手术切除病变后，发现第二前磨牙的牙根暴露。由于病变相关缺损的解剖结构，考虑采用冷冻干燥骨移植物和胶原膜联合再生治疗，这是首选的治疗方法。
活检显示符合 GCA 的组织学特征。术后 1 年的临床和影像学检查表明，软组织愈合和初始缺损的骨填充均无异常。文献回顾仅发现另一例与 GCA 相关的牙根暴露病例，且无先前关于再生治疗的报告。
在极少数情况下，GCA 病变可能导致牙根暴露。在这种情况下，可采用联合再生治疗方法来解决。
