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EUS 在 25 例连续患者(附有视频)的盆腔脓肿引流中的效果。

Effectiveness of EUS in drainage of pelvic abscesses in 25 consecutive patients (with video).

机构信息

Division of Gastroenterology-Hepatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA.

出版信息

Gastrointest Endosc. 2009 Dec;70(6):1121-7. doi: 10.1016/j.gie.2009.08.034.

Abstract

BACKGROUND

Preliminary evidence suggests that EUS is a minimally invasive alternative to surgery and percutaneous techniques for drainage of pelvic abscesses. The EUS 2008 Working Group identified the technique as a priority for research and recommended its validation in a larger cohort of patients.

OBJECTIVE

To evaluate the rates of technical and treatment success, rate of recurrence, and complications of EUS-guided drainage of a pelvic abscess in a large cohort of patients.

STUDY DESIGN

Observational study.

SETTING

Academic tertiary referral center.

PATIENTS

Consecutive patients referred for EUS-guided drainage of a pelvic abscess that was not amenable to drainage under US or CT guidance.

METHODS

In patients with an abscess that measured less than 8 cm in size, two 7F transrectal stents were deployed. In patients with an abscess that measured 8 cm or more in size, an additional 10F drainage catheter was deployed. All patients underwent follow-up CT at 36 hours to assess response to therapy. If the abscess had decreased in size by more than 50%, the drainage catheters were discontinued and patients were discharged from the hospital. The stents were then retrieved by sigmoidoscopy at 2 weeks.

MAIN OUTCOME MEASUREMENTS

We evaluated the rates of technical and treatment success, rate of recurrence, and complications of the EUS-based approach. Technical success was defined as the ability to drain the abscess under EUS guidance. Treatment success was defined as symptom relief in association with complete resolution of the abscess on follow-up CT at 2 weeks. Recurrence was defined as the need for repeat EUS-guided drainage of a pelvic abscess within 90 days after the stent retrieval.

RESULTS

The procedure was technically successful in all 25 patients (100%) in whom it was attempted, and no complications were encountered. Mean size of the abscess was 68.5 x 52.4 mm. In addition to transrectal stents, a drainage catheter was deployed in 10 patients. Treatment was successful in 24 (96%) of 25 patients. The mean duration of the postprocedure hospital stay was 3.2 days. At a mean follow-up of 189 days (range 93-817), all 24 patients were doing well without abscess recurrence.

CONCLUSIONS

EUS is a minimally invasive, safe, and effective technique that affords long-term benefit for patients undergoing pelvic abscess drainage.

摘要

背景

初步证据表明,EUS 是一种微创替代手术和经皮技术,用于引流盆腔脓肿。EUS 2008 工作组将该技术确定为研究的重点,并建议在更大的患者队列中验证其有效性。

目的

评估在大样本患者中,EUS 引导下引流盆腔脓肿的技术和治疗成功率、复发率和并发症发生率。

研究设计

观察性研究。

设置

学术三级转诊中心。

患者

连续转介至 EUS 引导下引流不适合 US 或 CT 引导下引流的盆腔脓肿的患者。

方法

对于大小小于 8cm 的脓肿,放置两条 7F 经直肠支架。对于大小为 8cm 或更大的脓肿,放置一条额外的 10F 引流导管。所有患者均在 36 小时内行 CT 随访以评估治疗反应。如果脓肿大小减少超过 50%,则停止引流导管并将患者从医院出院。然后在 2 周时通过乙状结肠镜取出支架。

主要观察指标

我们评估了基于 EUS 的方法的技术和治疗成功率、复发率和并发症发生率。技术成功定义为能够在 EUS 引导下引流脓肿。治疗成功定义为症状缓解并在 2 周的 CT 随访中完全消退。复发定义为在支架取出后 90 天内需要再次进行 EUS 引导下引流盆腔脓肿。

结果

在尝试进行该操作的 25 例患者中,所有患者(100%)均获得技术成功,未出现并发症。脓肿的平均大小为 68.5x52.4mm。除经直肠支架外,10 例患者还放置了引流导管。25 例患者中,24 例(96%)治疗成功。术后住院时间的平均时间为 3.2 天。在平均随访 189 天(范围为 93-817 天)后,所有 24 例患者均恢复良好,无脓肿复发。

结论

EUS 是一种微创、安全且有效的技术,可为接受盆腔脓肿引流的患者提供长期获益。

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