在淹溺创伤性低体温患者心肺复苏期间对人体微循环进行成像。

Imaging the human microcirculation during cardiopulmonary resuscitation in a hypothermic victim of submersion trauma.

机构信息

Department of Anesthesia, Intensive Care and Pain Management, St. Antonius Ziekenhuis, Koekoekslaan 1, 3435 CM, Nieuwegein, The Netherlands.

出版信息

Resuscitation. 2010 Jan;81(1):123-5. doi: 10.1016/j.resuscitation.2009.09.032. Epub 2009 Dec 5.

DOI:10.1016/j.resuscitation.2009.09.032

PMID:19963312

Abstract

The microcirculation is essential for delivery of oxygen and nutrients to tissue. However, the human microvascular response to cardiopulmonary resuscitation (CPR) is unknown. We report on the first use of sidestream dark field imaging to assess the human microcirculation during CPR with a mechanical chest compression/decompression device (mCPR). mCPR was able to provide microvascular perfusion. Capillary flow persisted even during brief mCPR interruption. However, indices of microvascular perfusion were low and improved vastly after return of spontaneous circulation. Microvascular perfusion was relatively independent from blood pressure. The microcirculation may be a useful monitor for determining the adequacy of CPR.

摘要

微循环对于向组织输送氧气和营养物质至关重要。然而，心肺复苏（CPR）对人体微血管的反应尚不清楚。我们首次报告了使用旁流暗场成像来评估机械胸部按压/减压装置（mCPR）进行 CPR 期间的人体微循环。mCPR 能够提供微血管灌注。即使在 mCPR 短暂中断期间，毛细血管血流也持续存在。然而，微血管灌注指数较低，在自主循环恢复后大大改善。微血管灌注相对独立于血压。微循环可能是确定 CPR 充分性的有用监测指标。