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在非均匀体模中实验性三维剂量曲线与通过MCNP5模拟获得的结果以及从商业治疗计划系统中提取的结果的比较。

Comparison of experimental 3D dose curves in a heterogeneous phantom with results obtained by MCNP5 simulation and those extracted from a commercial treatment planning system.

作者信息

Juste B, Miró R, Campayo J M, Díez S, Verdú G

机构信息

Polytechnic University of Valencia, Chemical and Nuclear Engineering Department, Valencia, Spain.

出版信息

Appl Radiat Isot. 2010 Apr-May;68(4-5):913-7. doi: 10.1016/j.apradiso.2009.09.063. Epub 2009 Oct 12.

Abstract

Commercial planning systems used in radiotherapy treatments use determinist correlations to evaluate dose distribution around regions of interest. Estimated dose with this type of planners can be problematic, especially when analyzing heterogeneous zones. The present work is focused in quantifying the dose distribution in a heterogeneous medium irradiated by a 6 MeV photon beam emitted by an Elekta Precise Radiotherapy Unit head. Dose mapping inside the heterogeneous water phantom has been simulated with the photon and electron transport with Monte Carlo computer code MCNP5 and also, using a commercial treatment planning software in the same irradiation conditions. The calculated results were compared with experimental relative dose curves. This comparison shows that inside the heterogeneity region, the commercial algorithms are not able to predict the variation of dose in the heterogeneous zones with the same precision as MCNP5.

摘要

放射治疗中使用的商业计划系统利用确定性关联来评估感兴趣区域周围的剂量分布。使用这类计划器估算的剂量可能存在问题,尤其是在分析异质区域时。目前的工作重点是量化由医科达精确放疗设备机头发射的6兆电子伏特光子束照射的异质介质中的剂量分布。已使用蒙特卡罗计算机代码MCNP5通过光子和电子输运模拟了异质水模体内部的剂量映射,并且在相同照射条件下使用了商业治疗计划软件进行模拟。将计算结果与实验相对剂量曲线进行了比较。该比较表明,在异质区域内,商业算法无法像MCNP5那样精确地预测异质区域内剂量的变化。

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