Parkin J M, Bridges J, Sloper K S, Warner J O, Pinching A J
Department of Immunology, St. Mary's Hospital Medical School, London, UK.
Scand J Immunol. 1991 Jan;33(1):89-95. doi: 10.1111/j.1365-3083.1991.tb02495.x.
Polymorphonuclear cell function tests were performed in 340 patients with recurrent unexplained infections. Serum-dependent defects in phagocytosis and intracellular killing of Candida albicans (Candida opsonin and procidin defects) were specifically associated with susceptibility to recurrent pyogenic infections, Candida opsonin defects occurring in 12.7% and Candida procidin defects in 20.8% of patients compared with 3.7% of healthy controls. Saccharomyces cerevisiae opsonin deficiencies were also found frequently in patients with recurrent infections, being present in 18.2% compared with 7.4% controls, although not specifically in those with pyogenic infection.
对340例不明原因复发性感染患者进行了多形核细胞功能测试。血清依赖性吞噬和白色念珠菌细胞内杀伤缺陷（念珠菌调理素和促杀菌素缺陷）与复发性化脓性感染易感性显著相关，12.7%的患者存在念珠菌调理素缺陷，20.8%的患者存在念珠菌促杀菌素缺陷，而健康对照者为3.7%。复发性感染患者中也经常发现酿酒酵母调理素缺乏，18.2%的患者存在该情况，而对照者为7.4%，不过并非化脓性感染患者所特有。
