Riviere P J La, Vargas P, Fu G, Meng L J
Department of Radiology, University of Chicago, Chicago, IL, USA.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:1000-3. doi: 10.1109/IEMBS.2009.5333568.
This paper presents new approaches to accelerating X-ray fluorescence tomography (XFCT) that are grounded in both novel image acquisition strategies that improve the quality of the data acquired and in image reconstruction strategies that reduce the amount of data acquired. First, we introduce an alternative imaging scheme that uses an emission tomography (ET) system to collect the fluorescence photons representing an entire 2D slice or volumetric projection of the object at one time. Preliminary results indicate that this could achieve a ten to hundredfold improvement in imaging speed. Secondly, novel image reconstruction algorithms are introduced that allow for improved quantitative accuracy as well as for imaging of regions of interest, which will lead to further reduction in data-acquisition time.
本文提出了加速X射线荧光断层扫描（XFCT）的新方法，这些方法基于两种策略，一种是改进采集数据质量的新型图像采集策略，另一种是减少采集数据量的图像重建策略。首先，我们引入了一种替代成像方案，该方案使用发射断层扫描（ET）系统一次收集代表物体整个二维切片或体积投影的荧光光子。初步结果表明，这可以使成像速度提高10到100倍。其次，引入了新颖的图像重建算法，这些算法可以提高定量精度，并能够对感兴趣区域进行成像，这将进一步减少数据采集时间。
