Tsiknakis M, Sfakianakis S, Zacharioudakis G, Umakis L, Kanterakis A, Potamias G, Kafetzopoulos D
Institute of Computer Science, Foundation for Research and Technology-Hellas, Heraklion, Crete, Greece.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:5625-8. doi: 10.1109/IEMBS.2009.5333787.
Recent advances in the field of bioinformatics present a number of challenges in the secure and efficient management and analysis of biological data resources. Workflow technologies aim to assist scientists and domain experts in the design of complex, long running, data and computing intensive experiments that involve many data processing and analysis tasks with the objective of generating new knowledge or formulate new hypothesis. In this paper we present a bioinformatics workflow authoring and execution environment that intends to greatly facilitate the whole lifecycle of such experiments. Emphasis is given on the security and ethical requirements of these scenarios and the corresponding technological response. In addition we present our semantic framework used for supporting specific user-requirements related to the reasoning and inference capabilities of the environment.
生物信息学领域的最新进展给生物数据资源的安全高效管理与分析带来了诸多挑战。工作流技术旨在协助科学家和领域专家设计复杂、耗时久、数据和计算密集型的实验,这些实验涉及许多数据处理和分析任务,目的是产生新知识或形成新假设。在本文中,我们展示了一个生物信息学工作流创作与执行环境,该环境旨在极大地便利此类实验的整个生命周期。重点关注这些场景的安全和伦理要求以及相应的技术应对措施。此外,我们还展示了用于支持与环境的推理能力相关的特定用户需求的语义框架。