Hickey M, Samuels N, Randive N, Langford R, Kyriacou P A
Engineering and Mathematical Sciences, City University, London, UK. m.hickey@ city.ac.uk
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:1505-8. doi: 10.1109/IEMBS.2009.5334159.
There is a need for a reliable and continuous monitoring of abdominal organ oxygen saturation (SpO(2)). Splanchnic ischemia may ultimately lead to cellular hypoxia and necrosis and may well contribute to the development of multiple organ failures and increased mortality. A new prototype reflectance fiber optic photoplethysmographic sensor and signal processing system was evaluated on six anaesthetized patients undergoing elective laparotomy. PPG signals were obtained from various organs, including large and small bowel, liver, and stomach. The normalized amplitudes of the splanchnic PPG signals were in good agreement with those obtained from the periphery using an identical fiber optic sensor. Furthermore, average SpO(2) values were in good agreement and showed correlation with those obtained from a commercial system. These preliminary results suggest that a miniaturized 'indwelling' fiber optic sensor may be a suitable method for pre-operative and post-operative evaluation of splanchnic organ SpO(2) and their health.
需要对腹部器官的氧饱和度（SpO₂）进行可靠且持续的监测。内脏缺血最终可能导致细胞缺氧和坏死，并很可能促使多器官功能衰竭的发生以及死亡率的增加。对一种新型的反射式光纤光电容积脉搏波传感器及信号处理系统在六名接受择期剖腹手术的麻醉患者身上进行了评估。从包括大肠、小肠、肝脏和胃在内的各种器官获取了光电容积脉搏波（PPG）信号。使用相同的光纤传感器，内脏PPG信号的归一化幅度与从外周获取的信号高度一致。此外，平均SpO₂值高度一致，并且与从商业系统获得的值具有相关性。这些初步结果表明，一种小型化的“植入式”光纤传感器可能是术前和术后评估内脏器官SpO₂及其健康状况的合适方法。
