Shimayoshi Takao, Amano Akira, Matsuda Tetsuya
ASTEM Research Institute of Kyoto, Kyoto 600-8813, Japan.
Annu Int Conf IEEE Eng Med Biol Soc. 2009;2009:2343-6. doi: 10.1109/IEMBS.2009.5335041.
Some models of cellular physiological functions are formulated as ordinary differential equations that contain multiple systems of simultaneous nonlinear equations. Simulation of such a model described in a declarative representation format requires determination of equations to be simultaneously solved with specification of independent and parameter variables in the model. In this report, a method for extracting systems of simultaneous equations in a cell model is presented. The present method analyzes a graph representation of a model and extracts the subgraphs that represent equation systems to be simultaneously solved, by efficiently interactive selection of independent variables of the model.
一些细胞生理功能模型被表述为包含多个联立非线性方程组的常微分方程。以声明式表示格式描述的此类模型的模拟需要确定要联立求解的方程，并指定模型中的自变量和参数变量。在本报告中，提出了一种在细胞模型中提取联立方程组的方法。该方法通过对模型自变量的高效交互式选择，分析模型的图形表示，并提取表示要联立求解的方程组的子图。
