[A case of HIV coinfected with hepatitis B virus treated by entecavir].

作者信息

Yamada Akihiro, Sako Akahito, Nishimura So, Nakashima Ryo, Ogami Toshiko, Fujiya Keiichi, Tsuda Naonori, Asayama Naoki, Yada Tomoyuki, Shirai Kiyokazu, Akazawa Naoki, Sakurai Toshiyuki, Yago Yuzo, Nagata Naoyoshi, Oshima Takao, Yokoi Chizu, Sasajima Keita, Kobayakawa Masao, Akiyama Junichi, Imamura Masatoshi, Yanase Mikio, Uemura Naomi, Masaki Naohiko

机构信息

Division of Gastroenterology, Toyama Hospital, International Medical Center of Japan, Japan.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2009 Dec;106(12):1758-63.

PMID:19966518

Abstract

A 45-year-old male active homosexual was given a diagnosis of HIV-1 and acute hepatitis B in August 2007. Since his liver function became rapidly impaired, anti-HBV therapy with oral administration of entecavir (ETV) was started, and resulted in a favorable outcome. However, serum concentration of HIV-RNA decreased by log 1.26 within 60 days, which strongly suggested the inhibition of HIV proliferation by ETV. To prevent the appearance of mutated HIV, novel therapeutic strategies should be established in HIV/HBV-coinfected patients.

摘要